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A Meta-Analytic Review of the Preventive Treatment of Recurrences of Febrile Seizures J Pediatr 131:922-925, Rantala,H.,et al, 1997 See this aricle in Pubmed Article Abstract A meta-analysis of all published randomized,placebo-controlled trials of the preventive treatment of febrile seizures published in English;45 articles were found but only 9 trials were randomized and placebo- controlled-4 using phenobarbital,3 diazepam,1 pyridoxine and 1 phenytoin. In one of the phenobarbital trials,valproate was also compared with placebo.Because both agents found to be effective in prevention of recurrent febrile seizures have known adverse effects,prophylaxis of febrile seizures cannot be recommended.

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(click to filter results - removes previous filter) anticonvulsants children prevention of neurologic disorders seizure seizure,children seizure,febrile seizure,prevention of seizure,treatment of treatment of neurologic disorder

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